Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11527342 | 0.98 | LMNA (0.30) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL11527248 | 0.72 | GABRR1 (0.34) | LMNATSHRPAX8KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11522121 | 0.71 | GABRR1 (0.33) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL10852907 | 0.70 | — | — | |
| SCHEMBL11522484 | 0.69 | LMNA (0.31) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL11530603 | 0.68 | XDH (0.32) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL11526158 | 0.65 | XDH (0.38) | LMNA | |
| SCHEMBL11662702 | 0.65 | — | — | |
| SCHEMBL4790338 | 0.65 | TSHR (0.31) | LMNATSHRPAX8KDM4EALDH1A1 | |
| SCHEMBL6348112 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166860-A | TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA | WILLIAM H. RORER, INC. (US) | 1979-09-04 | — | — | US | claimed |
| US-4166860-A | TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA | WILLIAM H. RORER, INC. (US) | 1979-09-04 | — | — | US | disclosed |