Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPX4 | P36969 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523311 | 0.85 | GPX4 (0.42) | GPX4LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11521735 | 0.85 | GPX4 (0.42) | GPX4LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11742782 | 0.77 | GPX4 (0.39) | GPX4ALDH1A1ELANE | |
| SCHEMBL11523282 | 0.77 | GPX4 (0.39) | GPX4ALDH1A1ELANE | |
| SCHEMBL11522399 | 0.77 | GPX4 (0.39) | GPX4ALDH1A1ELANE | |
| SCHEMBL11746547 | 0.77 | GPX4 (0.39) | GPX4ALDH1A1ELANE | |
| SCHEMBL11524953 | 0.77 | GPX4 (0.39) | GPX4ALDH1A1ELANE | |
| SCHEMBL11742201 | 0.75 | POLB (0.39) | LMNARAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL11522884 | 0.73 | PTGS2 (0.43) | GPX4LMNAALDH1A1MAPT | |
| SCHEMBL11737460 | 0.71 | GPX4 (0.39) | GPX4LMNARAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172079-A | Preparation of 4-nitroisoxazoles | TEXACO INC. (US) | 1979-10-23 | — | — | US | disclosed |