Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523151 | 0.75 | GPX4 (0.43) | POLBF2PLAUELANEALDH1A1 | |
| SCHEMBL10985014 | 0.72 | ALDH1A1 (0.51) | POLBF2PLAUELANEALDH1A1 | |
| SCHEMBL10991337 | 0.72 | RAB9A (0.48) | POLBALDH1A1RAB9APAX8MAPT | |
| SCHEMBL280227 | 0.69 | PTPN1 (0.48) | POLBALDH1A1RAB9APAX8MAPT | |
| SCHEMBL10993287 | 0.69 | RAB9A (0.46) | POLBALDH1A1RAB9APAX8MAPT | |
| SCHEMBL13316479 | 0.68 | PTPN1 (0.49) | POLBALDH1A1RAB9APAX8MAPT | |
| SCHEMBL10994126 | 0.68 | RAB9A (0.55) | POLBALDH1A1RAB9APAX8MAPT | |
| SCHEMBL1753233 | 0.65 | TARBP2 (0.46) | POLBELANEALDH1A1RAB9AMAPT | |
| SCHEMBL11833687 | 0.65 | MAPK13 (0.47) | POLBF2PLAUELANEALDH1A1 | |
| SCHEMBL13714272 | 0.64 | ALDH1A1 (0.62) | POLBF2PLAUELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061651-A | Preparation of 3,5-disubstituted-4-nitroisoxazoles | TEXACO INC. (US) | 1977-12-06 | — | — | US | disclosed |