Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524636 | 0.95 | ALDH1A1 (0.46) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11327576 | 0.79 | MAPT (0.57) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11841332 | 0.79 | HPGD (0.59) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11524967 | 0.79 | MAPT (0.50) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11523260 | 0.78 | AOC3 (0.53) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11525672 | 0.78 | NPC1 (0.49) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL11524969 | 0.77 | CHRNB4 (0.54) | MAPTALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL11520957 | 0.76 | MAPT (0.53) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11524956 | 0.76 | MAPT (0.47) | MAPTALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11564516 | 0.76 | MAPT (0.47) | MAPTALDH1A1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |