Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.40 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.40 |
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | F2R | P25116 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523524 | 0.86 | NPC1 (0.37) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11526357 | 0.86 | MEN1 (0.46) | RAB9ANPC1KMT2AMEN1ATM | |
| SCHEMBL13771799 | 0.75 | KMT2A (0.38) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11523668 | 0.75 | PIK3CA (0.43) | RAB9ANPC1KMT2AKDM4E | |
| SCHEMBL11524161 | 0.72 | RAB9A (0.39) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11522634 | 0.72 | RAB9A (0.48) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14642747 | 0.72 | KDM4E (0.44) | KMT2ASMN1; SMN2CYP1A2KDM4EL3MBTL1 | |
| SCHEMBL11525111 | 0.70 | ATM (0.39) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11523521 | 0.70 | PDE10A (0.38) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11521495 | 0.69 | PIK3CA (0.42) | RAB9ANPC1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |