Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524161 | 0.82 | RAB9A (0.39) | ATMRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11523355 | 0.81 | TYK2 (0.37) | RAB9ANPC1MEN1KMT2AMAPT | |
| SCHEMBL11525157 | 0.80 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11372439 | 0.75 | ALDH1A1 (0.43) | L3MBTL1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11523668 | 0.74 | PIK3CA (0.43) | RAB9ANPC1KMT2AKDM4EMAPK1 | |
| SCHEMBL11524059 | 0.72 | TRPV1 (0.42) | ATMRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11526201 | 0.72 | TYK2 (0.45) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11373899 | 0.71 | NPC1 (0.45) | L3MBTL1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL11523346 | 0.70 | RAB9A (0.40) | ATML3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11521578 | 0.69 | KDM4E (0.38) | ATMRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |