Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525111 | 0.82 | ATM (0.39) | RAB9AGBA1NPC1LMNAMAPT | |
| SCHEMBL11523668 | 0.76 | PIK3CA (0.43) | RAB9ANPC1PIK3CAMAPK8MAPK9 | |
| SCHEMBL11523355 | 0.75 | TYK2 (0.37) | RAB9AGBA1NPC1MAPTKMT2A | |
| SCHEMBL11525157 | 0.73 | MAPT (0.48) | RAB9AGBA1NPC1HTTLMNA | |
| SCHEMBL11373899 | 0.73 | NPC1 (0.45) | RAB9ANPC1ALOX15HTTGAA | |
| SCHEMBL11523346 | 0.72 | RAB9A (0.40) | RAB9ANPC1GAAKMT2AMEN1 | |
| SCHEMBL7598432 | 0.71 | RAB9A (0.54) | RAB9AGBA1NPC1HTTMAPT | |
| SCHEMBL11523444 | 0.71 | MAPT (0.39) | RAB9ANPC1HTTLMNAMAPT | |
| SCHEMBL11526201 | 0.70 | TYK2 (0.45) | RAB9ANPC1MAPTGAAKMT2A | |
| SCHEMBL11526049 | 0.70 | KMT2A (0.42) | RAB9ANPC1HTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |