Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTP4A2 | Q12974 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11520987 | 0.97 | HSD17B1 (0.62) | HSD17B1ALOX15S1PR1S1PR5HSD17B2 | |
| SCHEMBL11522626 | 0.97 | HSD17B1 (0.54) | HSD17B1ALOX15S1PR1S1PR5HSD17B2 | |
| SCHEMBL11520757 | 0.90 | HSD17B1 (0.58) | HSD17B1ALOX15S1PR1S1PR5HSD17B2 | |
| SCHEMBL9755135 | 0.84 | HSD17B1 (0.70) | HSD17B1HSD17B2ESR1ESR2ALDH1A1 | |
| SCHEMBL2595803 | 0.84 | S1PR1 (0.68) | HSD17B1ALOX15S1PR1S1PR5ALDH1A1 | |
| SCHEMBL11520044 | 0.81 | HSD17B1 (0.66) | HSD17B1HSD17B2ESR1ESR2ALDH1A1 | |
| SCHEMBL11522025 | 0.78 | HSD17B1 (0.58) | HSD17B1HSD17B2ESR1ESR2PTP4A3 | |
| SCHEMBL11522635 | 0.78 | HSD17B1 (0.58) | HSD17B1HSD17B2ESR1ESR2PTP4A3 | |
| SCHEMBL11524386 | 0.78 | HSD17B1 (0.58) | HSD17B1HSD17B2ESR1ESR2PTP4A3 | |
| SCHEMBL11518665 | 0.77 | HSD17B1 (0.58) | HSD17B1HSD17B2ESR1ESR2PTP4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174405-A | MITICIDES | UNIROYAL, INC. (US) | 1979-11-13 | — | — | US | disclosed |