Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | TNF | P01375 | 1/20 | 0.30 |
| ▸ | LITAF | Q99732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11843893 | 0.89 | MAT2A (0.38) | JAK2JAK1JAK3MAT2ACYP1A2 | |
| SCHEMBL11523573 | 0.86 | GSK3A (0.39) | JAK2JAK1JAK3MAT2A | |
| Hexazinone SCHEMBL4887146 | 0.84 | GSK3A (0.41) | JAK2JAK1JAK3MAT2A | |
| Hexazinone SCHEMBL66377 | 0.84 | GSK3A (0.41) | JAK2JAK1JAK3MAT2A | |
| SCHEMBL11841806 | 0.84 | GSK3A (0.41) | JAK2JAK1JAK3MAT2A | |
| SCHEMBL11841518 | 0.84 | GSK3A (0.41) | JAK2JAK1JAK3MAT2A | |
| SCHEMBL11841234 | 0.83 | MAT2A (0.39) | MAT2ACYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL11847766 | 0.82 | MAT2A (0.34) | MAT2ACYP1A2CASP1CASP7HSD17B10 | |
| SCHEMBL11869846 | 0.82 | PIK3CA (0.30) | — | |
| SCHEMBL11844702 | 0.80 | OPRM1 (0.33) | MAT2ACYP1A2CASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3983116-A | Herbicidal triazines | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-28 | — | — | US | disclosed |