Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523734 | 1.00 | TSHR (0.40) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL11437545 | 0.82 | TSHR (0.50) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL8006377 | 0.76 | — | — | |
| SCHEMBL8006379 | 0.76 | — | — | |
| SCHEMBL24268019 | 0.75 | TSHR (0.43) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL13063715 | 0.75 | TSHR (0.50) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3067341 | 0.75 | TSHR (0.43) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL143364 | 0.71 | TSHR (0.50) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL19508782 | 0.70 | TSHR (0.43) | TSHRHCAR2SMN1; SMN2HPGDNPC1 | |
| SCHEMBL6272695 | 0.70 | TAS2R38 (0.46) | TSHRHCAR2SMN1; SMN2HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160866-A | CROSSLINKERS FOR NATURAL AND SYNTHETIC RUBBERS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-07-10 | — | — | US | disclosed |