Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11437545 | 0.86 | TSHR (0.50) | TSHRHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL24268019 | 0.79 | TSHR (0.43) | TSHRHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL3067341 | 0.79 | TSHR (0.43) | TSHRCRBNHPGDNPC1CYP1A2 | |
| SCHEMBL24635151 | 0.77 | TSHR (0.48) | TSHRCRBNHPGDNPC1CYP1A2 | |
| SCHEMBL2932266 | 0.77 | TSHR (0.42) | TSHRHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL11625351 | 0.77 | TSHR (0.33) | TSHRCRBNSMN1; SMN2TAS2R38ALDH1A1 | |
| SCHEMBL11523739 | 0.75 | TSHR (0.40) | TSHRHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL11523734 | 0.75 | TSHR (0.40) | TSHRHPGDNPC1CYP1A2CYP2D6 | |
| SCHEMBL28642429 | 0.75 | CRBN (0.31) | TSHRCRBN | |
| SCHEMBL143364 | 0.75 | TSHR (0.50) | TSHRHPGDNPC1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100311757-A1 | Salarins And Tulearins, Compositions And Uses Thereof | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2010-12-09 | — | — | US | disclosed |
| CN-1228337-C | Carbamic acid derivs. and their use as metabotropic glutamate receptor ligands | HOFFMANN LA ROCHE (CH) | 2005-11-23 | — | — | CN | disclosed |
| CN-1347406-A | Carbamic acid derivs. and their use as metabotropic glutamate receptor ligands | HOFFMANN LA ROCHE (CH) | 2002-05-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311757-A1 | Salarins And Tulearins, Compositions And Uses Thereof | SFXN1, SPG11, SPAST | TSHR 3263/4885CRBN 3953/4885HPGD 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.