SCHEMBL11523800

SCHEMBL11523800

C=CC(C)=O.CCC(CC)NC(O)=S.NC(O)=S

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP8 P22894 1/20 0.35
CA9 Q16790 1/20 0.35
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16628367 0.81 CA12 (0.35) CA12CA1CA2MMP1MMP2
SCHEMBL16628486 0.81 CA12 (0.35) CA12CA1CA2MMP1MMP2
SCHEMBL3613760 0.77
SCHEMBL1304699 0.71 TAS1R3 (0.35)
SCHEMBL10905874 0.70
SCHEMBL5170699 0.69 TSHR (0.56) ALDH1A1CA12CA1CA2MMP1
SCHEMBL8601541 0.68 PLA2G2C (0.36) CA1CA2LMNA
SCHEMBL11607745 0.68 TAS2R38 (0.34)
SCHEMBL16931565 0.67 PLA2G2C (0.35) CA1CA2LMNA
SCHEMBL16931574 0.67 PLA2G2C (0.35) CA1CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4148795-A Dithiocarbamate ester bactericides and fungicides AMERICAN CYANAMID COMPANY (US) 1979-04-10 US disclosed
US-4038288-A DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1977-07-26 US disclosed
US-4011230-A DITHIOCARBAMATE ESTER BACTERICIDES AND FUNGICIDES AMERICAN CYANAMID COMPANY (US) 1977-03-08 US disclosed