SCHEMBL11524159

SCHEMBL11524159

OP(O)C(NC(c1ccccc1)c1ccccc1)c1ccc(Cl)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.47
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
CACNA2D1 P54289 1/20 0.43
CACNA1B Q00975 1/20 0.43
CACNB1 Q02641 1/20 0.43
SLC6A9 P48067 5/20 0.41
SLC6A5 Q9Y345 4/20 0.41
IDO1 P14902 2/20 0.41
TDO2 P48775 2/20 0.41
AKT1 P31749 1/20 0.41
SLC6A2 P23975 2/20 0.40
SLC6A4 P31645 2/20 0.40
SLC6A3 Q01959 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
CHRM1 P11229 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11523341 0.89 MTOR (0.41) MEN1KMT2ACACNA2D1CACNA1BCACNB1
SCHEMBL11525863 0.83 LMNA (0.50) CNR1MEN1KMT2ASLC6A9TDP1
SCHEMBL9511748 0.81 IDO1 (0.52) CNR1MEN1KMT2ACACNA2D1CACNA1B
SCHEMBL11522951 0.80 CACNA2D1 (0.47) CNR1MEN1KMT2ACACNA2D1CACNA1B
SCHEMBL11525667 0.79 ALDH1A1 (0.42) MEN1KMT2ATDP1
SCHEMBL11522959 0.77 UGT2B7 (0.43) MEN1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL11527224 0.76 POLB (0.55) MEN1KMT2ACACNA1BIDO1
SCHEMBL11526405 0.73 CFTR (0.54) SLC6A2SLC6A4SLC6A3
SCHEMBL21836281 0.73 MEN1 (0.52) CNR1MEN1KMT2ASLC6A9SLC6A5
SCHEMBL21836282 0.73 MEN1 (0.52) CNR1MEN1KMT2ASLC6A9SLC6A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4147780-A α-Amino-phosphonous acids for inhibiting bacteria and yeast CIBA-GEIGY CORPORATION (US) 1979-04-03 US disclosed