Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.54 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523341 | 0.82 | MTOR (0.41) | CFTRGOPCSMN1; SMN2KDM4ECYP3A4 | |
| SCHEMBL21836264 | 0.75 | KDM4E (0.65) | CFTRGOPCSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL21836265 | 0.75 | KDM4E (0.65) | CFTRGOPCSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL30664391 | 0.75 | KDM4E (0.65) | CFTRGOPCSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL11524159 | 0.73 | CNR1 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11525863 | 0.73 | LMNA (0.50) | SMN1; SMN2CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL11977430 | 0.72 | CFTR (0.51) | CFTRGOPCSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL11522959 | 0.71 | UGT2B7 (0.43) | SLC6A2SLC6A4SLC6A3CYP1A2CYP3A4 | |
| SCHEMBL23970129 | 0.70 | CFTR (0.58) | CFTRGOPCSMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL11525667 | 0.70 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EPOLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147780-A | α-Amino-phosphonous acids for inhibiting bacteria and yeast | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |