Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | F2R | P25116 | 5/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11526086 | 0.97 | KDM4E (0.47) | KDM4EALDH1A1MAPK1GAAALOX15 | |
| SCHEMBL11527179 | 0.88 | HSD17B10 (0.45) | KDM4EALDH1A1HDAC6MEN1KMT2A | |
| SCHEMBL11524196 | 0.85 | HDAC6 (0.41) | KDM4EALDH1A1MAPK1HDAC6EPHX2 | |
| SCHEMBL11521271 | 0.84 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPK1GAAALOX15 | |
| SCHEMBL11525828 | 0.84 | RAB9A (0.46) | KDM4EALDH1A1MAPK1GAAF2R | |
| SCHEMBL11524531 | 0.80 | RAB9A (0.48) | KDM4EALDH1A1MAPK1GAAF2R | |
| SCHEMBL11690843 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1MAPK1GAAALOX15 | |
| SCHEMBL11411088 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPK1GAAALOX15F2R | |
| SCHEMBL11520770 | 0.78 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPK1GAAALOX15 | |
| SCHEMBL30020925 | 0.78 | LMNA (0.54) | KDM4EALDH1A1ICMTALBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139528-A | Water-insoluble monoazo dyestuffs which is a diazotized 6-cyano-2:4-dinitroaniline coupled to a m-acylamino-substituted aniline | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-02-13 | — | — | US | disclosed |