Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL115271 | 0.90 | KMT2A (0.35) | PDE5AALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL113857 | 0.88 | ALDH1A1 (0.38) | PDE5AALDH1A1SMN1; SMN2TACR1HSD17B10 | |
| SCHEMBL113848 | 0.87 | GRM1 (0.36) | ALDH1A1TACR1HPGDKDM4EKCNH2 | |
| SCHEMBL115259 | 0.86 | PDE5A (0.33) | PDE5AALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL116138 | 0.86 | PDE5A (0.36) | PDE5AALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL115235 | 0.81 | BRD4 (0.38) | ALDH1A1SMN1; SMN2TACR1HPGDKDM4E | |
| SCHEMBL116175 | 0.79 | HEXA (0.40) | ALDH1A1TACR1HSD17B10HPGDKDM4E | |
| SCHEMBL115155 | 0.79 | KDM4E (0.35) | PDE5AALDH1A1LMNASMN1; SMN2TSHR | |
| SCHEMBL115354 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HPGDKDM4EEPHB4 | |
| SCHEMBL115128 | 0.78 | MEN1 (0.38) | ALDH1A1LMNASMN1; SMN2TSHRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120058893-A1 | HERBICIDALLY ACTIVE KETOSULTAMS AND DIKETOPYRIDINES | KHK, KCNA1, KCNA2 | PDE5A 2487/4885ALDH1A1 274/4885LMNA 3651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.