Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.57 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.52 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.52 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564904 | 0.88 | GLO1 (0.63) | NFE2L2GLO1MAPTALDH1A1CA1 | |
| SCHEMBL10989985 | 0.87 | GLO1 (0.61) | NFE2L2GLO1MAPTALDH1A1CA1 | |
| SCHEMBL10983993 | 0.78 | GLO1 (0.66) | NFE2L2GLO1MAPTALDH1A1CA1 | |
| SCHEMBL14306012 | 0.75 | MAPT (0.76) | NFE2L2TXNRD1TXNRD3TXNRD2MAPT | |
| SCHEMBL4184895 | 0.75 | MAOA (0.55) | NFE2L2MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10896764 | 0.75 | GLO1 (0.61) | NFE2L2GLO1MAPTALDH1A1CA1 | |
| SCHEMBL10896757 | 0.75 | GLO1 (0.61) | NFE2L2GLO1MAPTALDH1A1CA1 | |
| SCHEMBL4184889 | 0.75 | MAOA (0.55) | NFE2L2MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4184894 | 0.75 | MAOA (0.55) | NFE2L2MAPTALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL1194705 | 0.74 | NFE2L2 (0.65) | NFE2L2TXNRD1TXNRD3TXNRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |