Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158161 | 0.82 | ALDH1A1 (0.43) | TDP1MEN1KMT2ACYP11B1CYP3A4 | |
| SCHEMBL28797149 | 0.82 | ALOX15 (0.59) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL31158162 | 0.82 | ALDH1A1 (0.59) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL16208442 | 0.80 | TDP1 (0.56) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL1421973 | 0.75 | NPC1 (0.40) | MEN1KMT2AHSP90AA1ALDH1A1HSD17B10 | |
| SCHEMBL6565672 | 0.75 | MEN1 (0.60) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL17229026 | 0.73 | MAP4K4 (0.32) | HSP90AA1 | |
| SCHEMBL23855 | 0.72 | TDP1 (1.00) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL29349835 | 0.72 | TDP1 (1.00) | TDP1MEN1KMT2ACYP17A1CYP19A1 | |
| SCHEMBL31158156 | 0.72 | MAP4K4 (0.52) | MEN1KMT2ACYP17A1CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159262-A | POLYIMIDES, POLYBENZIMIDAZOLES, POLYQUINOXALINES, POLYIMIDAZOPYRROLONES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR, NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1979-06-26 | — | — | US | disclosed |
| US-4061856-A | TO 1,3,5-TRIAZINES, SULFONIC, SULFINIC, PHOSPHONIC OR PHOSPHINIC ACID OR METAL ACETYLACETONATE CATALYST | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) | 1977-12-06 | — | — | US | disclosed |