SCHEMBL11524311

SCHEMBL11524311

O=C(Cl)c1ccc(-c2nnc(C3CCCCC3)s2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.43
NPC1 O15118 7/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
TP53 P04637 1/20 0.43
CSNK2A2 P19784 2/20 0.42
CSNK2A1 P68400 2/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPSR1 Q6W5P4 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HRH3 Q9Y5N1 1/20 0.40
PTGER3 P43115 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 5/20 0.40
GFER P55789 1/20 0.39
CSNK2B P67870 1/20 0.39
CASP3 P42574 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525875 0.87 CSNK2A2 (0.56) RAB9ANPC1SMN1; SMN2TP53CSNK2A2
SCHEMBL7334743 0.73 CSNK2A2 (0.56) SMN1; SMN2CSNK2A2CSNK2A1KMT2ACSNK2B
SCHEMBL11524489 0.72 CSNK2A2 (0.51) RAB9ANPC1SMN1; SMN2CSNK2A2CSNK2A1
SCHEMBL11226995 0.72 ALDH1A1 (0.47) RAB9ANPC1SMN1; SMN2TP53MEN1
SCHEMBL11526587 0.72 CSNK2A2 (0.47) RAB9ANPC1SMN1; SMN2CSNK2A2CSNK2A1
SCHEMBL17185387 0.72 GAA (0.53) RAB9ANPC1SMN1; SMN2TP53CSNK2A2
SCHEMBL31227666 0.71 CSNK2A2 (0.46) RAB9ANPC1SMN1; SMN2CSNK2A2CSNK2A1
SCHEMBL1692419 0.70 HDAC8 (0.59) SMN1; SMN2KMT2AALDH1A1
SCHEMBL7336218 0.69 PDE4D (0.53) RAB9ANPC1SMN1; SMN2CSNK2A2CSNK2A1
SCHEMBL17184890 0.69 HDAC1 (0.37) RAB9ANPC1SMN1; SMN2CSNK2A2CSNK2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed