SCHEMBL11526587

SCHEMBL11526587

O=C(Cl)c1ccc(-c2nnc(Cl)s2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 8/20 0.47
CSNK2A1 P68400 8/20 0.47
CSNK2B P67870 1/20 0.47
KDM4E B2RXH2 3/20 0.44
MGAM O43451 1/20 0.44
GAA P10253 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
NOTUM Q6P988 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
MAPT P10636 1/20 0.44
HDAC1 Q13547 3/20 0.43
HDAC2 Q92769 2/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524489 0.82 CSNK2A2 (0.51) CSNK2A2CSNK2A1CSNK2BKDM4ESMN1; SMN2
SCHEMBL31227666 0.81 CSNK2A2 (0.46) CSNK2A2CSNK2A1CSNK2BSMN1; SMN2RAB9A
SCHEMBL8707903 0.78 KDM4E (0.67) KDM4EMGAMGAASIMGAM2
SCHEMBL11524776 0.77 RAB9A (0.49) CSNK2A2CSNK2A1CSNK2BKDM4ESMN1; SMN2
SCHEMBL11523160 0.77 ALDH1A1 (0.58) CSNK2A2CSNK2A1CSNK2BKDM4EGAA
SCHEMBL11524897 0.77 RAB9A (0.58) CSNK2A2CSNK2A1KDM4ESMN1; SMN2MAPT
SCHEMBL11523167 0.74 SMN1; SMN2 (0.40) KDM4EGAASMN1; SMN2MAPTRAB9A
SCHEMBL7451976 0.74 CSNK2A2 (0.40) CSNK2A2CSNK2A1CSNK2BKDM4ESMN1; SMN2
SCHEMBL7451980 0.74 CSNK2A2 (0.40) CSNK2A2CSNK2A1CSNK2BKDM4ESMN1; SMN2
SCHEMBL11091755 0.73 KDM4E (0.50) KDM4EMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed