SCHEMBL11525875

SCHEMBL11525875

O=C(O)c1ccc(-c2nnc(C3CCCCC3)s2)cc1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 12/20 0.56
CSNK2A1 P68400 12/20 0.56
CSNK2B P67870 1/20 0.54
PDE4D Q08499 1/20 0.48
PDE7A Q13946 1/20 0.48
NR1H4 Q96RI1 1/20 0.44
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
RECQL P46063 1/20 0.43
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524311 0.87 RAB9A (0.43) CSNK2A2CSNK2A1CSNK2BNPC1RAB9A
SCHEMBL7334743 0.86 CSNK2A2 (0.56) CSNK2A2CSNK2A1CSNK2BPDE4DPDE7A
SCHEMBL7611472 0.78 CSNK2A2 (0.49) CSNK2A2CSNK2A1CSNK2BNR1H4MEN1
SCHEMBL7360994 0.78 CSNK2A2 (0.49) CSNK2A2CSNK2A1CSNK2BNR1H4MEN1
SCHEMBL14646221 0.78 CSNK2A2 (0.76) CSNK2A2CSNK2A1CSNK2BNR1H4
SCHEMBL11599027 0.78 CSNK2A2 (0.76) CSNK2A2CSNK2A1CSNK2BNR1H4
Hydrochloric Acid SCHEMBL6538467 0.75 CSNK2A2 (0.50) CSNK2A2CSNK2A1CSNK2BMEN1KMT2A
SCHEMBL17185387 0.73 GAA (0.53) CSNK2A2CSNK2A1PDE4DPDE7ANPC1
SCHEMBL17656010 0.73 CSNK2A2 (0.69) CSNK2A2CSNK2A1CSNK2BNR1H4NPC1
SCHEMBL6134406 0.72 HRH3 (0.53) CSNK2A2CSNK2A1CSNK2BPDE4DPDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4159985-A Heterocyclic phenyl ester ultraviolet stabilizers EASTMAN KODAK COMPANY (US) 1979-07-03 US disclosed
US-4140674-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1979-02-20 US disclosed
US-4020080-A Oxadiazolylphenyl aromatic ester compounds and their use as ultraviolet stabilizer in organic compositions EASTMAN KODAK COMPANY (US) 1977-04-26 US disclosed