Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | QDPR | P09417 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6590672 | 0.87 | QDPR (0.54) | HTR2CSIGMAR1QDPRTLR9TLR7 | |
| SCHEMBL7394377 | 0.84 | HTR2C (0.60) | HTR2CSIGMAR1QDPRKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL4789235 | 0.82 | HTR2C (0.61) | HTR2CSIGMAR1QDPRKDM4EMAPT | |
| SCHEMBL7479570 | 0.82 | HTR2C (0.52) | HTR2CSIGMAR1QDPRTLR9TLR7 | |
| SCHEMBL5464711 | 0.79 | NPC1 (0.50) | MAPTTDP1 | |
| SCHEMBL15649593 | 0.77 | ADRA2A (0.47) | HTR2CKDM4EGAAMAPTTHRB | |
| SCHEMBL6278676 | 0.75 | HTR2C (0.57) | HTR2CSIGMAR1QDPRHTR6 | |
| SCHEMBL14704745 | 0.75 | QDPR (0.51) | HTR2CSIGMAR1QDPRKDM4EGAA | |
| SCHEMBL30431801 | 0.75 | HTR2C (0.66) | HTR2CSIGMAR1QDPRHTR6 | |
| SCHEMBL4790435 | 0.75 | HTR2C (0.66) | HTR2CSIGMAR1QDPRHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166853-A | Antihypertensive 7-trifluoromethyl-4-aminoquinolones | THE UPJOHN COMPANY (US) | 1979-09-04 | — | — | US | disclosed |