Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525837 | 0.91 | CNR1 (0.42) | GRM5MAPTGHSRRAB9ANPC1 | |
| SCHEMBL11526310 | 0.90 | DHODH (0.43) | GRM5MAPTGHSRRAB9ANPC1 | |
| SCHEMBL11523714 | 0.90 | RAB9A (0.43) | MAPTGHSRRAB9ANPC1JAK2 | |
| SCHEMBL3665409 | 0.89 | MAPT (0.38) | GAAMAPTGHSRRAB9ANPC1 | |
| SCHEMBL11524415 | 0.89 | GAA (0.46) | GAAGRM5MAPTITGB1ITGA4 | |
| SCHEMBL11370506 | 0.88 | GAA (0.42) | CHRNA7GAAGHSRRAB9ANPC1 | |
| SCHEMBL11521131 | 0.88 | CHRNA7 (0.42) | CHRNA7MAPTGHSRRAB9ANPC1 | |
| SCHEMBL11525153 | 0.88 | MAPT (0.50) | CHRNA7GAAMAPTGHSRITGB1 | |
| SCHEMBL11522564 | 0.87 | ITGB1 (0.41) | MAPTGHSRITGB1ITGA4ITGB7 | |
| SCHEMBL11526021 | 0.84 | PLK1 (0.41) | GAAITGB1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |