SCHEMBL3665409

SCHEMBL3665409

Cc1nc(NC(=O)NC(=O)c2c(Cl)cccc2Cl)cnc1-c1ccc(Br)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.38
GHSR Q92847 1/20 0.38
KMT2A Q03164 4/20 0.38
RAB9A P51151 3/20 0.38
MEN1 O00255 3/20 0.38
GBA1 P04062 1/20 0.38
POLB P06746 1/20 0.38
PTGFR P43088 2/20 0.37
TYK2 P29597 3/20 0.37
JAK2 O60674 2/20 0.37
JAK1 P23458 2/20 0.37
TRPV1 Q8NER1 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
PPARG P37231 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525837 0.91 CNR1 (0.42) MAPTGHSRKMT2ARAB9AMEN1
SCHEMBL11526310 0.90 DHODH (0.43) MAPTGHSRKMT2ARAB9AMEN1
SCHEMBL11523714 0.90 RAB9A (0.43) MAPTGHSRKMT2ARAB9AMEN1
SCHEMBL11522591 0.90 MAPT (0.39) MAPTGHSRKMT2ARAB9APTGFR
SCHEMBL11524435 0.89 CHRNA7 (0.40) MAPTGHSRRAB9AGBA1TYK2
SCHEMBL11523035 0.89 MAPT (0.37) MAPTGHSRRAB9APOLBTYK2
SCHEMBL11524059 0.89 TRPV1 (0.42) MAPTKMT2ARAB9AMEN1GBA1
SCHEMBL7628324 0.88 PCTP (0.42) GHSRKMT2ARAB9APOLBTDP1
SCHEMBL11525153 0.88 MAPT (0.50) MAPTGHSRKMT2ARAB9AMEN1
SCHEMBL11522082 0.88 TYK2 (0.40) MAPTGHSRKMT2ARAB9AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0845944-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AG (DE) 1998-06-10 EP claimed
WO-1997006687-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-27 WO claimed
US-4160834-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-07-10 US claimed
US-8741874-B2 Insecticidal compositions with disinfectant BAYER CROPSCIENCE LP (US) 2014-06-03 US disclosed
CN-101703048-B Microencapsulated insect growth regulating composition SUMITOMO CHEMICAL CO 2013-03-27 CN disclosed
US-8263099-B2 Insect growth regulating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
EP-2227089-A2 INSECTICIDAL COMPOSITIONS WITH DISINFECTANT Bayer Cropscience LP (US) 2010-09-15 EP disclosed
CN-101703048-A Microencapsulated insect growth regulating composition SUMITOMO CHEMICAL CO 2010-05-12 CN disclosed
CN-100581360-C Insect growth regulating composition SUMITOMO CHEMICAL CO 2010-01-20 CN disclosed
US-20090246239-A1 INSECT GROWTH REGULATING COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-01 US disclosed
WO-2009061341-A2 INSECTICIDAL COMPOSITIONS WITH DISINFECTANT BAYER CROPSCIENCE LP (US) 2009-05-14 WO disclosed
WO-1997006687-A1 ACTIVE SUBSTANCE COMBINATIONS COMPRISING PYRETHROIDS AND INSECT-DEVELOPMENT INHIBITORS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-27 WO disclosed
US-5420163-A Insecticides or miticides CIBA-GEIGY (US) 1995-05-30 US disclosed
US-5135953-A Oral or injections; cattle, swine, poultry CIBA-GEIGY (US) 1992-08-04 US disclosed
EP-0211004-A1 USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS RHONE-POULENC NEDERLAND B.V. (NL) 1987-02-25 EP disclosed
WO-1986003941-A1 USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS UNION CARBIDE CORPORATION (US) 1986-07-17 WO disclosed
US-RE30563-E Preparation of benzoylureas ELI LILLY AND COMPANY (US) 1981-03-31 US disclosed
US-4160834-A INSECTICIDES ELI LILLY AND COMPANY (US) 1979-07-10 US disclosed
US-4133956-A Preparation of benzoylureas ELI LILLY AND COMPANY (US) 1979-01-09 US disclosed
US-4083977-A Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas ELI LILLY AND COMPANY (US) 1978-04-11 US disclosed