Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | GHSR | Q92847 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525837 | 0.89 | CNR1 (0.42) | MAPTGHSRCNR1MEN1KMT2A | |
| SCHEMBL8667778 | 0.89 | GHSR (0.51) | MAPTGHSRCNR1MEN1KMT2A | |
| SCHEMBL11526310 | 0.89 | DHODH (0.43) | MAPTGHSRCNR1MEN1KMT2A | |
| SCHEMBL11523714 | 0.88 | RAB9A (0.43) | MAPTGHSRCNR1MEN1KMT2A | |
| SCHEMBL3665409 | 0.88 | MAPT (0.38) | MAPTGHSRCNR1MEN1KMT2A | |
| SCHEMBL11524435 | 0.88 | CHRNA7 (0.40) | MAPTGHSRCHRNA7NPC1RAB9A | |
| SCHEMBL11521131 | 0.86 | CHRNA7 (0.42) | MAPTGHSRMEN1KMT2ACHRNA7 | |
| SCHEMBL11522564 | 0.85 | ITGB1 (0.41) | MAPTGHSRKMT2AMAPK1ITGB1 | |
| SCHEMBL11524415 | 0.85 | GAA (0.46) | MAPTMEN1KMT2ANPC1KDM4E | |
| SCHEMBL11170854 | 0.83 | MAPT (0.52) | MAPTGHSRMEN1KMT2ACHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | claimed |
| US-4160834-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1979-07-10 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |