Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11690330 | 0.86 | NPC1 (0.45) | RAB9AHDAC3CA12CA1CA2 | |
| SCHEMBL11522204 | 0.85 | POLB (0.47) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11644543 | 0.83 | KMT2A (0.43) | RAB9AHDAC3MEN1KMT2AALDH1A1 | |
| SCHEMBL11519775 | 0.81 | BDKRB1 (0.46) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11518679 | 0.80 | DHODH (0.48) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL11642876 | 0.78 | CA12 (0.42) | HDAC3CA12CA1CA2CA9 | |
| SCHEMBL11788004 | 0.78 | HDAC3 (0.43) | RAB9AHDAC3ALDH1A1HDAC1EPHX1 | |
| SCHEMBL11648352 | 0.77 | RAB9A (0.40) | RAB9AHDAC3MEN1KMT2AALDH1A1 | |
| SCHEMBL11648011 | 0.77 | HDAC3 (0.41) | HDAC3MEN1KMT2AALDH1A1HDAC1 | |
| SCHEMBL11640906 | 0.77 | RAB9A (0.41) | RAB9AHDAC3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |