Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11640165 | 0.92 | HDAC3 (0.37) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11640682 | 0.84 | POLB (0.50) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11690330 | 0.80 | NPC1 (0.45) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11788004 | 0.80 | HDAC3 (0.43) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11640906 | 0.79 | RAB9A (0.41) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11644543 | 0.79 | KMT2A (0.43) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 | |
| SCHEMBL11647190 | 0.79 | GAA (0.42) | RAB9AHDAC3HDAC1ALDH1A1HTT | |
| SCHEMBL11640137 | 0.79 | PTGER4 (0.44) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL11645788 | 0.78 | CA1 (0.49) | HDAC3HDAC1ALDH1A1HTT | |
| SCHEMBL11524716 | 0.77 | RAB9A (0.38) | RAB9AHDAC3HDAC1EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088780-A | ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4024176-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
| US-3993682-A | Substituted phenylguanidines and processes for their preparation and use | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |