Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11635788 | 0.99 | CNR2 (0.52) | CNR2ALDH1A1TDP1LMNATHRB | |
| SCHEMBL11525232 | 0.86 | ALDH1A1 (0.53) | CNR2ALDH1A1TDP1LMNAKMT2A | |
| SCHEMBL11527071 | 0.85 | ALDH1A1 (0.52) | CNR2ALDH1A1TDP1LMNAKMT2A | |
| SCHEMBL11636062 | 0.85 | ALDH1A1 (0.64) | CNR2ALDH1A1TDP1LMNATHRB | |
| SCHEMBL11632430 | 0.84 | ALDH1A1 (0.66) | CNR2ALDH1A1TDP1LMNATHRB | |
| SCHEMBL11632341 | 0.81 | POLB (0.42) | ALDH1A1TDP1TSHRKMT2ACYP2C19 | |
| SCHEMBL11528664 | 0.78 | KMT2A (0.51) | CNR2ALDH1A1TDP1LMNATSHR | |
| SCHEMBL11632049 | 0.78 | POLB (0.44) | TDP1TSHRKMT2ACYP2C19MEN1 | |
| SCHEMBL30484960 | 0.76 | ALDH1A1 (0.64) | ALDH1A1TDP1LMNATHRBTSHR | |
| SCHEMBL11634436 | 0.76 | MEN1 (0.50) | CNR2ALDH1A1TDP1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4083979-A | Thiazolidine derivatives and their use as salidiuretics | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-04-11 | — | — | US | disclosed |