Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478775 | 0.87 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Sulbenox SCHEMBL110252 | 0.84 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11261499 | 0.84 | CA12 (0.45) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Sulbenox SCHEMBL11740934 | 0.84 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11523831 | 0.84 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11483627 | 0.84 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11530459 | 0.84 | LMNA (0.48) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11266499 | 0.83 | NPC1 (0.42) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11484374 | 0.83 | KMT2A (0.53) | LMNARAB9ASMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL11484369 | 0.81 | LMNA (0.43) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156670-A | UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-29 | — | — | US | claimed |
| US-4036979-A | ANIMAL GROWTH RATE ACCELERATOR | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | claimed |