Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulbenox SCHEMBL110252 | 1.00 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11535620 | 0.92 | LMNA (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11261499 | 0.85 | CA12 (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11746594 | 0.84 | LMNA (0.40) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11525613 | 0.84 | LMNA (0.46) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11478775 | 0.83 | LMNA (0.61) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11523831 | 0.82 | LMNA (0.45) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11554785 | 0.82 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11546081 | 0.82 | L3MBTL1 (0.42) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA | |
| SCHEMBL11741414 | 0.82 | LMNA (0.39) | SMN1; SMN2NPC1RAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4060627-A | Substituted tetrahydroiminobenzo(b)thien-4-ylureas as novel growth promoting compounds for animals | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | claimed |