Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478775 | 0.85 | LMNA (0.61) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11554785 | 0.84 | NPC1 (0.42) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11525613 | 0.84 | LMNA (0.46) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11261499 | 0.82 | CA12 (0.45) | LMNANPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL11523831 | 0.82 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11483627 | 0.82 | LMNA (0.45) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL11533734 | 0.81 | LMNA (0.66) | LMNANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11484122 | 0.80 | LMNA (0.69) | LMNANPC1RAB9ASMN1; SMN2TSHR | |
| Sulbenox SCHEMBL110252 | 0.80 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 | |
| Sulbenox SCHEMBL11740934 | 0.80 | SMN1; SMN2 (0.44) | LMNANPC1RAB9ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156670-A | UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-29 | — | — | US | claimed |
| US-4036979-A | ANIMAL GROWTH RATE ACCELERATOR | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | claimed |