Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.55 |
| ▸ | AKT1 | P31749 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527338 | 0.88 | ALDH1A1 (0.52) | CFDPOLBKMT2AMAPTALDH1A1 | |
| SCHEMBL9218825 | 0.83 | TDP1 (0.52) | POLBKMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL19663825 | 0.81 | CFD (0.61) | CFDAKT1POLBKMT2AMAPT | |
| SCHEMBL11527226 | 0.80 | CNR2 (0.54) | POLBKMT2AMAPTALDH1A1GAA | |
| SCHEMBL27441423 | 0.77 | AKT1 (0.58) | CFDAKT1ALDH1A1GAANPC1 | |
| SCHEMBL11513699 | 0.76 | ALDH1A1 (0.46) | POLBKMT2AMAPTALDH1A1GAA | |
| SCHEMBL7410935 | 0.75 | POLB (0.62) | POLBKMT2AMAPTALDH1A1NPC1 | |
| SCHEMBL9588937 | 0.75 | AKT1 (0.59) | CFDAKT1ALDH1A1GAAKDM4E | |
| SCHEMBL11515657 | 0.75 | GAA (0.45) | POLBMAPTALDH1A1GAANPC1 | |
| SCHEMBL28399335 | 0.75 | ALDH1A1 (0.65) | POLBMAPTALDH1A1GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141995-A | Ketone derivatives | LILLY INDUSTRIES LIMITED (GB) | 1979-02-27 | — | — | US | disclosed |