Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9209426 | 0.86 | TDP1 (0.62) | TDP1TSHRPTGDR2POLBMAPT | |
| SCHEMBL9214962 | 0.84 | PTGDR2 (0.57) | TDP1TSHRPTGDR2POLBMAPT | |
| SCHEMBL11525710 | 0.83 | CFD (0.55) | TSHRPOLBPPARDPPARGPPARA | |
| SCHEMBL11527338 | 0.82 | ALDH1A1 (0.52) | POLBPPARDPPARGPPARAMAPT | |
| SCHEMBL9214221 | 0.82 | TDP1 (0.58) | TDP1TSHRPTGDR2POLBMAPT | |
| SCHEMBL14419478 | 0.82 | PTGDR2 (0.57) | TDP1TSHRPTGDR2POLBMAPT | |
| SCHEMBL8398940 | 0.80 | PTGDR2 (0.70) | TDP1TSHRPTGDR2MAPTPTGDR | |
| SCHEMBL15331250 | 0.79 | PTGDR2 (0.66) | TDP1TSHRPTGDR2POLBPPARD | |
| SCHEMBL14419539 | 0.79 | PTGDR2 (0.69) | TDP1TSHRPTGDR2PPARDMAPT | |
| SCHEMBL14419297 | 0.79 | PTGDR2 (0.57) | TDP1TSHRPTGDR2MAPTPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |