Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28950593 | 1.00 | NAAA (0.35) | NAAAALDH1A1CYP3A4TSHRFAAH | |
| SCHEMBL11526143 | 1.00 | NAAA (0.35) | NAAAALDH1A1CYP3A4TSHRFAAH | |
| SCHEMBL31323878 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TSHREPHX2MAPTRAB9A | |
| SCHEMBL31323822 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TSHREPHX2MAPTRAB9A | |
| SCHEMBL31613126 | 0.91 | ALDH1A1 (0.41) | ALDH1A1TSHREPHX2MAPTRAB9A | |
| SCHEMBL27487204 | 0.90 | EPHX2 (0.39) | ALDH1A1TSHREPHX2MAPT | |
| SCHEMBL27488981 | 0.84 | SMN1; SMN2 (0.38) | ALDH1A1EPHX2MAPT | |
| SCHEMBL3477367 | 0.84 | MAPT (0.38) | NAAAALDH1A1FAAHEPHX2MAPT | |
| SCHEMBL28347972 | 0.83 | — | — | |
| SCHEMBL1296678 | 0.80 | NAAA (0.59) | NAAAALDH1A1TSHRFAAHPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4162328-A | PESTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1979-07-24 | — | — | US | disclosed |