Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477539 | 0.91 | GAA (0.37) | MAPTGAACYP2C9POLBHPGD | |
| SCHEMBL10479724 | 0.88 | NAAA (0.44) | MAPTGAACYP2C9NAAAPOLB | |
| SCHEMBL10479725 | 0.88 | NAAA (0.44) | MAPTGAACYP2C9NAAAPOLB | |
| SCHEMBL10073834 | 0.87 | GAA (0.43) | MAPTGAACYP2C9NAAAPOLB | |
| SCHEMBL3477855 | 0.86 | MEN1 (0.42) | MAPTGAACYP2C9NAAAPOLB | |
| SCHEMBL14926581 | 0.86 | ALDH1A1 (0.47) | MAPTGAANAAAPOLBHPGD | |
| SCHEMBL10480056 | 0.86 | NAAA (0.47) | MAPTGAANAAAEPHX2PKM | |
| SCHEMBL21475280 | 0.86 | NAAA (0.51) | MAPTGAANAAAPOLBHPGD | |
| SCHEMBL14926573 | 0.86 | MAPT (0.39) | MAPTGAANAAAPOLBHPGD | |
| SCHEMBL20032684 | 0.86 | ACHE (0.40) | MAPTGAANAAAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| US-8372307-B2 | Cyclohexylene reactive mesogens and their applications | MERCK PATENT GMBH (DE) | 2013-02-12 | — | — | US | disclosed |
| EP-2087067-B1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| EP-2087067-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | Merck Patent GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
| WO-2008061606-A1 | CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS | MERCK PATENT GMBH (DE) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100103366-A1 | Cyclohexylene Reactive Mesogens and Their Applications | CUTA, MC1R, CTSG | MAPT 745/4885GAA 3465/4885CYP2C9 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.