Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 3/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | FNTA | P49354 | 1/20 | 0.55 |
| ▸ | FNTB | P49356 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525870 | 1.00 | AR (0.71) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL18506541 | 0.94 | AR (0.64) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL18506544 | 0.91 | NR3C2 (0.68) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL18506540 | 0.91 | PGR (0.60) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL1247962 | 0.90 | PGR (0.87) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL10380853 | 0.90 | PGR (0.87) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL10380855 | 0.90 | PGR (0.87) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL11244221 | 0.85 | AR (0.63) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL6944506 | 0.85 | AR (0.63) | ARPGRCHRM1HIF1ALMNA | |
| SCHEMBL835740 | 0.85 | AR (0.68) | ARPGRCHRM1HIF1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154748-A | Phosphate catalyzed acylation of steroidal tertiary alcohols | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | claimed |
| US-4154748-A | Phosphate catalyzed acylation of steroidal tertiary alcohols | THE UPJOHN COMPANY (US) | 1979-05-15 | — | — | US | disclosed |