Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.64 |
| ▸ | PGR | P06401 | 3/20 | 0.64 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525865 | 0.94 | AR (0.71) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL11525870 | 0.94 | AR (0.71) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL18506544 | 0.89 | NR3C2 (0.68) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL18506540 | 0.89 | PGR (0.60) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL22605938 | 0.88 | PGR (0.51) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL10380853 | 0.84 | PGR (0.87) | ARPGRCHRM1CYP3A4HIF1A | |
| SCHEMBL10380855 | 0.84 | PGR (0.87) | ARPGRCHRM1CYP3A4HIF1A | |
| SCHEMBL1247962 | 0.84 | PGR (0.87) | ARPGRCHRM1CYP3A4HIF1A | |
| SCHEMBL6944506 | 0.82 | AR (0.63) | ARPGRCHRM1CYP3A4ALDH1A1 | |
| SCHEMBL11244221 | 0.82 | AR (0.63) | ARPGRCHRM1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170043024-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | UNIVERSITY OF MASSACHUSETTS | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170043024-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | DCLRE1B, RTCB, RNASE1 | AR 2144/4885PGR 3592/4885CHRM1 4764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.