Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 8/20 | 0.68 |
| ▸ | PGR | P06401 | 4/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 3/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.57 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525870 | 0.91 | AR (0.71) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL11525865 | 0.91 | AR (0.71) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL3049344 | 0.89 | NR3C2 (0.84) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL321463 | 0.89 | NR3C2 (0.84) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL18506541 | 0.89 | AR (0.64) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL18506540 | 0.89 | PGR (0.60) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL20553192 | 0.89 | NR3C2 (0.82) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL23456329 | 0.86 | NR3C2 (0.70) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL122186 | 0.85 | NR3C2 (0.79) | NR3C2PGRNR3C1HIF1AKMT2A | |
| SCHEMBL6565022 | 0.84 | AR (0.82) | NR3C2PGRNR3C1HIF1AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200339983-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | UNIVERSITY OF MASSACHUSETTS | 2020-10-29 | — | — | US | disclosed |
| US-20190185855-A1 | CONJUGATED OLIGONUCLEOTIDES | UNIVERSITY OF MASSACHUSETTS | 2019-06-20 | — | — | US | disclosed |
| US-20170043024-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | UNIVERSITY OF MASSACHUSETTS | 2017-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339983-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | DCLRE1B, RTCB, RNASE1 | NR3C2 3351/4885PGR 3592/4885NR3C1 2841/4885 |
| US-20170043024-A1 | BIOACTIVE CONJUGATES FOR OLIGONUCLEOTIDE DELIVERY | DCLRE1B, RTCB, RNASE1 | NR3C2 3351/4885PGR 3592/4885NR3C1 2841/4885 |
| US-20190185855-A1 | CONJUGATED OLIGONUCLEOTIDES | DCLRE1B, DCLRE1A, TNNC1 | NR3C2 1917/4885PGR 2957/4885NR3C1 1384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.