Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | HTR3A | P46098 | 2/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.30 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MPO | P05164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10947114 | 0.76 | GAA (0.40) | GAASLC9A1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11311574 | 0.68 | CYP3A4 (0.38) | GAAALDH1A1KDM4ECYP3A4TSHR | |
| SCHEMBL11523520 | 0.65 | CYP19A1 (0.40) | GAAALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL7581003 | 0.65 | ALDH1A1 (0.37) | GAAALDH1A1KDM4EGLASMN1; SMN2 | |
| SCHEMBL25174825 | 0.64 | ABL1 (0.46) | ALDH1A1KDM4ECYP1A2SMN1; SMN2LMNA | |
| SCHEMBL7073779 | 0.62 | GAA (0.57) | GAAALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL30498666 | 0.62 | GAA (0.57) | GAAALDH1A1KDM4ECYP1A2CYP2D6 | |
| SCHEMBL64092 | 0.61 | GAA (1.00) | GAAALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL2087687 | 0.59 | ALDH1A1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL6402873 | 0.59 | GAA (0.52) | GAAALDH1A1KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165319-A | Isoindoline pigments | CIBA-GEIGY CORPORATION (US) | 1979-08-21 | — | — | US | disclosed |