SCHEMBL11526356

SCHEMBL11526356

COc1ccc(/C=C/c2ccc(CO)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.59
TRPA1 O75762 1/20 0.59
KDM4E B2RXH2 3/20 0.58
CYP1A1 P04798 3/20 0.58
CYP1B1 Q16678 3/20 0.58
PTGS2 P35354 3/20 0.58
LMNA P02545 2/20 0.58
PTGS1 P23219 2/20 0.58
ALOX12 P18054 1/20 0.58
CYP1A2 P05177 3/20 0.57
ESR1 P03372 2/20 0.57
NQO2 P16083 2/20 0.57
ALOX5 P09917 2/20 0.57
AHR P35869 2/20 0.57
ABL1 P00519 1/20 0.57
TTR P02766 1/20 0.57
ABCB1 P08183 1/20 0.57
BCR P11274 1/20 0.57
CYP19A1 P11511 1/20 0.57
TUBB4A P04350 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11526358 1.00 RELA (0.59) RELATRPA1KDM4ECYP1A1CYP1B1
SCHEMBL20024711 0.94 RELA (0.53) RELATRPA1KDM4ECYP1A1CYP1B1
Anethole SCHEMBL15954631 0.91 LMNA (0.71) RELATRPA1KDM4ECYP1A1CYP1B1
Anethole SCHEMBL15954628 0.91 LMNA (0.71) RELATRPA1KDM4ECYP1A1CYP1B1
SCHEMBL806380 0.90 PTGS2 (0.49) RELATRPA1KDM4ECYP1A1CYP1B1
SCHEMBL17486898 0.90 KDM4E (0.55) RELATRPA1KDM4ECYP1A1CYP1B1
SCHEMBL27329 0.87 IDO1 (0.58) ALOX12CYP3A4TP53TSHRALDH1A1
SCHEMBL4181089 0.87 IDO1 (0.58) ALOX12CYP3A4TP53TSHRALDH1A1
SCHEMBL14665732 0.87 PTGS2 (0.62) RELATRPA1KDM4ECYP1A1CYP1B1
SCHEMBL15096130 0.87 CYP1A1 (0.67) KDM4ECYP1A1CYP1B1PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9120984-B2 Transition metal catalysts for hydrodesulfurization GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2015-09-01 US disclosed
US-20140174989-A1 TRANSITION METAL CATALYSTS FOR HYDRODESULFURIZATION GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2014-06-26 US disclosed
US-4153719-A Aromatic diketones STERLING DRUG INC. (US) 1979-05-08 US disclosed