Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.49 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.49 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.49 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.49 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.49 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892857 | 0.81 | TBXA2R (0.74) | TBXA2RTBXAS1 | |
| SCHEMBL11526469 | 0.78 | PSEN1 (0.47) | TBXA2RTBXAS1PSEN1PSEN2APH1B | |
| SCHEMBL1284358 | 0.77 | TBXA2R (0.79) | TBXA2RTBXAS1 | |
| SCHEMBL11413107 | 0.75 | PPARA (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Adipic Acid SCHEMBL15656104 | 0.75 | MAPT (0.64) | TBXAS1 | |
| Sebacic Acid SCHEMBL7203711 | 0.73 | MAPT (0.68) | TBXAS1 | |
| Azelaic Acid SCHEMBL31309960 | 0.73 | MAPT (0.68) | TBXAS1 | |
| Glutarate SCHEMBL28239405 | 0.72 | HDAC3 (0.63) | — | |
| SCHEMBL5416824 | 0.71 | PPARD (0.46) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11524276 | 0.71 | PSEN1 (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176194-A | ANTIINFLAMMATORY AGENTS; ANALGESICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |