Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 16/20 | 0.79 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892857 | 0.95 | TBXA2R (0.74) | TBXA2RTBXAS1PPARA | |
| SCHEMBL9602658 | 0.87 | TBXA2R (0.81) | TBXA2RTBXAS1 | |
| SCHEMBL9602647 | 0.87 | TBXA2R (0.81) | TBXA2RTBXAS1 | |
| SCHEMBL9602582 | 0.79 | TBXA2R (0.85) | TBXA2RTBXAS1 | |
| SCHEMBL9602592 | 0.79 | TBXA2R (0.85) | TBXA2RTBXAS1 | |
| SCHEMBL3883360 | 0.79 | TBXA2R (0.54) | TBXA2RTBXAS1 | |
| Benzylamine SCHEMBL11526467 | 0.77 | TBXA2R (0.53) | TBXA2RTBXAS1 | |
| SCHEMBL9601444 | 0.77 | TBXA2R (0.76) | TBXA2RTBXAS1 | |
| SCHEMBL9601449 | 0.77 | TBXA2R (0.76) | TBXA2RTBXAS1 | |
| SCHEMBL8613026 | 0.77 | TBXA2R (0.51) | TBXA2RTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410161-B2 | Thioxanthone ring system derivatives | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2013-04-02 | — | — | US | disclosed |
| US-20120088810-A1 | THIOXANTHONE RING SYSTEM DERIVATIVES | NATIONAL DEFENSE MEDICAL CENTER (TW) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088810-A1 | THIOXANTHONE RING SYSTEM DERIVATIVES | TST, TXN, XDH | TBXA2R 7/4885TBXAS1 5/4885PPARA 1615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.