Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15656106 | 0.78 | MEN1 (0.53) | MAPT | |
| Benzylamine SCHEMBL11526467 | 0.78 | TBXA2R (0.53) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL28239404 | 0.75 | GAA (0.55) | — | |
| SCHEMBL21611670 | 0.72 | STING1 (0.54) | HTT | |
| SCHEMBL8842303 | 0.71 | MEN1 (0.49) | MAPT | |
| SCHEMBL8905338 | 0.70 | EPHX2 (0.56) | L3MBTL1HPGD | |
| SCHEMBL10892857 | 0.70 | TBXA2R (0.74) | TBXAS1TBXA2RPPARA | |
| Hydrochloric Acid SCHEMBL8843485 | 0.70 | MEN1 (0.47) | — | |
| SCHEMBL8843381 | 0.70 | MEN1 (0.73) | HTT | |
| SCHEMBL27653287 | 0.69 | L3MBTL1 (0.48) | L3MBTL1HTTMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176194-A | ANTIINFLAMMATORY AGENTS; ANALGESICS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |