Sebacic Acid

Sebacic Acid

SCHEMBL7203711

NCc1ccccc1.O=C(O)CCCCCCCCC(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
HDAC3 O15379 2/20 0.61
HDAC4 P56524 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC7 Q8WUI4 2/20 0.61
HDAC2 Q92769 2/20 0.61
HDAC10 Q969S8 2/20 0.61
HDAC11 Q96DB2 2/20 0.61
HDAC8 Q9BY41 2/20 0.61
HDAC6 Q9UBN7 2/20 0.61
HDAC9 Q9UKV0 2/20 0.61
HDAC5 Q9UQL6 2/20 0.61
SLC6A3 Q01959 2/20 0.61
MAPK1 P28482 1/20 0.61
ADRA1A P35348 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
LOXL2 Q9Y4K0 1/20 0.58
KEAP1 Q14145 1/20 0.54
TSHR P16473 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Azelaic Acid SCHEMBL31309960 1.00 MAPT (0.68) MAPTRXFP1HDAC3HDAC4HDAC1
Adipic Acid SCHEMBL15656104 0.98 MAPT (0.64) MAPTRXFP1HDAC3HDAC4HDAC1
Glutarate SCHEMBL28239405 0.94 HDAC3 (0.63) MAPTRXFP1HDAC3HDAC4HDAC1
Dodecanoate SCHEMBL27705448 0.91 GPR84 (0.59) MAPTRXFP1HDAC11TSHRMEN1
Heptanoate SCHEMBL2288500 0.91 GPR84 (0.59) MAPTRXFP1HDAC11TSHRMEN1
Stearic Acid SCHEMBL9345826 0.91 GPR84 (0.59) MAPTRXFP1HDAC11TSHRMEN1
Adipic Acid SCHEMBL272108 0.90 MAPT (0.55) MAPTRXFP1HDAC3HDAC4HDAC1
Benzylamine SCHEMBL29016376 0.89 LOXL2 (0.67) MAPTRXFP1HDAC3HDAC4HDAC1
Phenylbutanoic Acid SCHEMBL724890 0.88 HDAC1 (0.81) MAPTRXFP1HDAC3HDAC4HDAC1
Adipic Acid SCHEMBL5694409 0.88 MAPT (0.53) MAPTRXFP1HDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105874309-B Temperature control material 日油技研工业株式会社 2018-12-04 CN disclosed
US-9581501-B2 Temperature control material NIGK CORPORATION (JP) 2017-02-28 US disclosed
US-20160290871-A1 TEMPERATURE CONTROL MATERIAL NIGK CORPORATION (JP) 2016-10-06 US disclosed
US-9145514-B2 Temperature management indicator and structure having the same attached NICHIYU GIKEN KOGYO CO., LTD. (JP) 2015-09-29 US disclosed
EP-2554961-A1 TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED Nichiyu Giken Kogyo Co. Ltd. (JP) 2013-02-06 EP disclosed
US-20130014690-A1 TEMPERATURE MANAGEMENT INDICATOR AND STRUCTURE HAVING THE SAME ATTACHED NICHIYU GIKEN KOGYO CO., LTD. (JP) 2013-01-17 US disclosed
US-6602594-B2 Mixture of a granular or powdery heat-fusible substance and a granular or powdery dyestuff that can be diffused through dispersion or dissolution; indicators; microcapsules NICHIYU GIKEN KOGYO CO., LTD. (JP) 2003-08-05 US disclosed
US-20010044014-A1 Irreversible heat-sensitive composition NICHIYU GIKEN KOGYO CO., LTD. 2001-11-22 US disclosed
EP-1149880-A1 Irreversible heat-sensitive composition Nichiyu Giken Kogyo Co., Ltd. (JP) 2001-10-31 EP disclosed