SCHEMBL11526549

SCHEMBL11526549

Cc1cc(S(=O)(=O)NNC(N)=O)cc(C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.43
GAA P10253 3/20 0.42
ALDH1A1 P00352 3/20 0.42
MAPT P10636 2/20 0.42
POLB P06746 3/20 0.42
LMNA P02545 2/20 0.42
CYTH2 Q99418 1/20 0.41
BRD4 O60885 1/20 0.40
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
KMT2A Q03164 4/20 0.39
MEN1 O00255 3/20 0.39
BCAT1 P54687 1/20 0.39
KAT6A Q92794 2/20 0.38
RAB9A P51151 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CYP2C9 P11712 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525497 0.87 ACHE (0.40) GFERGAAALDH1A1MAPTPOLB
SCHEMBL11525953 0.87 CYP1A2 (0.42) GFERGAAALDH1A1MAPTPOLB
SCHEMBL11528792 0.79 GAA (0.42) GAAALDH1A1MAPTPOLBLMNA
SCHEMBL11525813 0.79 ALDH1A1 (0.43) GAAALDH1A1LMNACA1CA2
SCHEMBL11526686 0.76 CYP1A2 (0.50) GFERGAAALDH1A1MAPTLMNA
SCHEMBL125338 0.75 POLB (0.73) GAAALDH1A1MAPTPOLBLMNA
SCHEMBL8395741 0.74 KMT2A (0.54) GFERGAAALDH1A1POLBLMNA
SCHEMBL11512561 0.74 POLB (0.71) GAAALDH1A1MAPTPOLBLMNA
SCHEMBL1094124 0.73 ALDH1A1 (0.48) GFERGAAALDH1A1POLBLMNA
SCHEMBL5082897 0.72 GAA (0.49) GAAALDH1A1MAPTPOLBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164611-A ALSO ACT AS HEAT AND OXIDATION STABILIZER CIBA-GEIGY CORPORATION (US) 1979-08-14 US claimed
US-4164611-A ALSO ACT AS HEAT AND OXIDATION STABILIZER CIBA-GEIGY CORPORATION (US) 1979-08-14 US disclosed