SCHEMBL11528792

SCHEMBL11528792

CC(C)(C)c1cc(S(=O)(=O)NNC(N)=O)cc(C(C)(C)C)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.42
ALDH1A1 P00352 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
CA2 P00918 3/20 0.40
CA1 P00915 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
POLB P06746 2/20 0.39
TYR P14679 1/20 0.39
GABBR2 O75899 2/20 0.39
GABBR1 Q9UBS5 2/20 0.39
GLRA3 O75311 1/20 0.39
GLRB P48167 1/20 0.39
EGFR P00533 1/20 0.38
MEN1 O00255 1/20 0.37
GALR3 O60755 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 2/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11525953 0.91 CYP1A2 (0.42) GAAALDH1A1TDP1CA2CA1
SCHEMBL11526549 0.79 GFER (0.43) GAAALDH1A1TDP1CA2CA1
SCHEMBL11526963 0.79 SMN1; SMN2 (0.38) GAAALDH1A1TDP1CA2CA1
SCHEMBL11529072 0.78 CA2 (0.47) GAAALDH1A1TDP1CA2CA1
SCHEMBL11525921 0.76 KAT6A (0.33) GAAALDH1A1TDP1GABBR2GABBR1
SCHEMBL11525813 0.75 ALDH1A1 (0.43) GAAALDH1A1CA2CA1EGFR
SCHEMBL8768792 0.72 CA2 (0.52) GAAALDH1A1TDP1CA2CA1
SCHEMBL13522250 0.72 CA2 (0.56) GAAALDH1A1TDP1CA2CA1
SCHEMBL8395741 0.71 KMT2A (0.54) GAAALDH1A1TDP1CA2CA1
SCHEMBL11525497 0.71 ACHE (0.40) GAAALDH1A1CA2CA1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164611-A ALSO ACT AS HEAT AND OXIDATION STABILIZER CIBA-GEIGY CORPORATION (US) 1979-08-14 US disclosed