Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | CATSPER1 | Q8NEC5 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10478050 | 0.79 | MAPT (0.47) | PTGS2CATSPER1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1026251 | 0.77 | — | — | |
| SCHEMBL8463065 | 0.75 | PTGS2 (0.56) | PTGS2CATSPER1ALDH1A1KMT2AMEN1 | |
| SCHEMBL22245510 | 0.75 | PTGS2 (0.52) | PTGS2ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL6587237 | 0.73 | PKM (0.50) | PTGS2CATSPER1ALDH1A1KMT2AMEN1 | |
| SCHEMBL15891186 | 0.72 | ALDH1A1 (0.56) | CATSPER1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL5750757 | 0.72 | ALDH1A1 (0.53) | PTGS2ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL1790158 | 0.71 | — | — | |
| Benzophenone SCHEMBL2156249 | 0.69 | ALDH1A1 (0.74) | ALDH1A1KMT2AMEN1NPC1HPGD | |
| SCHEMBL17263069 | 0.69 | KMT2A (0.52) | ALDH1A1KMT2AMEN1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164395-A | USING A SULFONYL OXIME AS ACTIVATOR | FMC CORPORATION (US) | 1979-08-14 | — | — | US | disclosed |