Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | QPCT | Q16769 | 9/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11527369 | 1.00 | HRH4 (0.35) | HRH4QPCTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9809757 | 0.89 | BCHE (0.32) | HRH4BCHEACHE | |
| SCHEMBL9809754 | 0.89 | BCHE (0.32) | HRH4BCHEACHE | |
| SCHEMBL11215888 | 0.89 | BCHE (0.32) | HRH4BCHEACHE | |
| SCHEMBL11467208 | 0.81 | MIF (0.39) | HRH4QPCTCYP3A4CYP2D6CYP2C9 | |
| SCHEMBL10567477 | 0.80 | CYP1A2 (0.41) | HRH4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11158901 | 0.79 | DHPS (0.42) | HRH4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11158899 | 0.79 | DHPS (0.42) | HRH4CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL9777091 | 0.79 | HRH4 (0.32) | HRH4 | |
| SCHEMBL9777093 | 0.79 | HRH4 (0.32) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171325-A | Chemical process | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-10-16 | — | — | US | disclosed |