SCHEMBL115274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13077192	0.86	KMT2A (0.39)	LMNAKMT2AGFERPTGS2GRIN2B
	SCHEMBL3727130	0.86	CXCR3 (0.48)	LMNAKMT2AGFERPTGS2GRIN2B
	SCHEMBL114927	0.84	CHEK1 (0.40)	CHEK1GRIN2BSMN1; SMN2CXCR3KCNH2
	SCHEMBL163411	0.84	PTGS2 (0.42)	LMNAKMT2AGFERPTGS2SMN1; SMN2
	SCHEMBL115798	0.83	HTR1A (0.42)	LMNAKMT2AGFERPTGS2GRIN2B
	SCHEMBL114199	0.81	PTGS2 (0.42)	LMNAKMT2AGFERPTGS2SMN1; SMN2
	SCHEMBL112087	0.73	CYP1A2 (0.48)	LMNAKMT2AGFERSMN1; SMN2RAB9A
	SCHEMBL115019	0.73	SMN1; SMN2 (0.53)	LMNAKMT2ASMN1; SMN2RAB9AGAA
	SCHEMBL113751	0.73	CXCR3 (0.49)	CHEK1KMT2AGRIN2BSMN1; SMN2CXCR3
	SCHEMBL115583	0.72	CXCR3 (0.72)	LMNAKMT2AGRIN2BSMN1; SMN2CXCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.