Hydrazinecarboxamide

Hydrazinecarboxamide

SCHEMBL11527487

CC(C)c1cc(S(=O)(=O)O)cc(C(C)C)c1O.NNC(N)=O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
GAA P10253 4/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
EGFR P00533 1/20 0.39
GABRA1 P14867 4/20 0.39
GABRB1 P18505 4/20 0.39
GABRB2 P47870 1/20 0.39
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39
HTT P42858 2/20 0.38
LMNA P02545 1/20 0.38
ACHE P22303 1/20 0.38
NT5E P21589 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15033889 0.86 CA1 (0.54) ALDH1A1GAACA1CA2GABRA1
SCHEMBL15613397 0.78 GABRA1 (0.52) ALDH1A1GAACA1CA2GABRA1
SCHEMBL11525813 0.76 ALDH1A1 (0.43) ALDH1A1GAACA1CA2EGFR
SCHEMBL11525472 0.76 ACHE (0.53) ALDH1A1GAACA1CA2GABRA1
SCHEMBL11527495 0.73 ALDH1A1 (0.40) ALDH1A1GAACA1CA2EGFR
SCHEMBL6235189 0.73 CA1 (0.56) ALDH1A1GAACA1CA2GABRA1
SCHEMBL10351050 0.72 CA1 (0.47) ALDH1A1CA1CA2FABP3FABP4
SCHEMBL10301256 0.71 FABP3 (0.48) ALDH1A1GAACA1CA2FABP3
SCHEMBL27262232 0.70 GAA (0.57) ALDH1A1GAACA1CA2GABRA1
SCHEMBL11529037 0.70 GABRA1 (0.54) ALDH1A1GAACA1CA2GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4164611-A ALSO ACT AS HEAT AND OXIDATION STABILIZER CIBA-GEIGY CORPORATION (US) 1979-08-14 US disclosed